Endocrine Abstracts

A 68 yr old male with a history of type 2 diabetes presented with myalgia and girdle weakness affecting him on a frequent but episodic basis. Investigations confirmed Cyclical Cushing's Disease. Pituitary MRI was normal. Further investigations include bilateral inferior petrosal sinus sampling (BIPSS) which can help determine the origin of ACTH-dependent Cushing’s syndrome. After CRH-stimulation, a peak central to peripheral ACTH ratio of >3 suggests a pituitary ACTH ...

A 28-year-old man presented to his GP in Turkey complaining of fatigue. As part of his work up, serum PTH was assessed and was found to be markedly elevated at 29.9 pmol/l (normal range 1.6–6.8), with normal calcium, phosphate, alkaline phosphatase, renal function, 1,25- and 25-hydroxy vitamin D3 levels. A DEXA scan was normal and a Sestamibi scan did not reveal any parathyroid adenoma. Prior to any further investigations or treatment, he moved to the UK.<p class="abs...

Background: C-peptide is an amino-acid chain which is an equimolar marker of endogenous insulin. It is used to investigate the cause of non-diabetic hypoglycaemia and classification of diabetes. C-peptide can only be interpreted with a paired venous glucose <3 mmol/l for non-diabetic hypoglycaemia, and >4 mmol/l for diabetes classification.Aims and Objectives: To determine if: 1. C-peptide tests were requested for appropriate indication 2. Tests ...